Alpha-Thrombin (FIIa)

Thrombin (Activated Factor II)


Thrombin, also named activated factor II (FIIa), is a serine protease present in the coagulation cascade. Thrombin activates factor XI, VIII, V, XIII and fibrinogen.

Asnail provides human alpha-thrombin for anti-FIIa activity assay of heparin.


Origin Human plasma Purity ≥95%, by SDS-PAGE
Appearance white lyophilized powder E1%(OD280nm about 10
Molecular weight about 35 kDa Specific activity ≥ 1500 IU/mg
EC number Isoelectronic point 7


Alpha-thrombin can be used in many applications, such as:

  • Anti-factor Xa activity to anti-factor IIa activity ratios of heparin and LMWHs.
  • Anti-factor IIa activities of heparin and LMWHs.
  • Anti-factor IIa activities of heparin and LMWHs in human plasma.

Order information:

Cat. # Description Qty.
AS00-0131 Alpha-Thrombin, from Human Plasma 10×10 IU

Related Products:

Cat. # Description
AS00-0101 S-2238, Chromogenic Substrate for Thrombin
AS00-0121 Activated Factor X
AS00-0102 S-2765, Chromogenic Substrate for Factor Xa
AS00-0103 S-2222, Chromogenic Substrate for Factor Xa
AS00-0132 Human Antithrombin

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