Description
The activated factor X (FXa)-specific chromogenic substrate S-2765 is a short peptide covalently bound to pNA (4-nitroaniline). A free pNA will be cleaved off the peptide chain by activated factor X, thus enabling quantitive detection by a spectrophotometer.
Asnail provides S-2765 for anti-FXa activity assay of coagulants, such as heparin.
Properties:
| Origin | Synthesis | Appearance | white or light yellow lyophilized powder |
|---|---|---|---|
| CAS number | 115388-96-0 | Purity | ≥99%, by HPLC |
| Molecular formula | Z-D-Arg-Gly-Arg-pNA·2HCl | Solubility | ≥ 10 mg/mL (in pure water) |
| Molecular weight | 714.6 Da | Absorption coefficient | A405nm ≤ 0.120 [L/(g·cm)] |
Applications:
Chromogenic substrate S-2765 is mainly used for anti-FXa activity assay of coagulants, such as heparin, among other applications:
- Anti-factor Xa activity to anti-factor IIa activity ratios of heparin and LMWHs.
- Anti-factor Xa activities of heparin and LMWHs.
- Activities of antithrombin and coagulation factors.
- Anti-factor Xa activities of heparin and LMWHs in human plasma.
Order information:
| Cat. # | Description | Qty. |
|---|---|---|
| AS00-0102 | S-2765, Chromogenic Substrate for Factor Xa | 10×25 mg |
Related Products:
Asnail Chinese Website:www.asnailtech.com.cn
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